An intercostal nerve block is one of the techniques used to treat pain syndromes, whether acute or chronic, in the vicinity of the chest. In 1907, Heinrich Braun was the first to describe the procedure. Intercostal nerves course underneath the lower margins of the ribs. Intercostal nerve blocks require the injection of a local anesthetic, with or without a steroid, in the area adjacent to intercostal nerves. The procedure is part of an integrative approach to the treatment and management of pain. Intercostal nerve blocks are seldom the only treatment prescribed and are paired with other avenues of treatment such as anti-inflammatory medication, physical therapy (PT), anti-convulsive medication, oral or intravenous opioids (narcotics), occupational therapy (OT), and antidepressants.